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교수진

문효열 부교수

전공운동생리학
주소71-1동 407호
연락처880-7802
이메일skyman19@snu.ac.kr
연구분야
  • 운동 분자유전 및 생화학 / 운동과 암제어/ 운동과 생체 신호전달 – 엑소좀/ 운동과 피로/ 운동과 정서 및 인지/ 운동과 뇌혈관 질환

담당교과목
  • 트레이닝방법론, 운동생리학실험, 건강운동실험, 운동과 뇌신경과학 연구
학력
  • 서울대학교 사범대학 체육교육과 학사

  • 포항공과대학교 시스템생명공학 생체신호전달 석사

  • 포항공과대학교 시스템생명공학 생체신호전달 박사

경력
  • 現 서울대학교 체육교육과 부교수
  • 現 운동생리학회 학술위원, 편집위원, 이사
  • 現 대한스포츠과학-운동의학회 이사
  • 現 운동영양학회 부편집위원장, 국제이사
  • 現 뇌기반학습연구센터 센터장
  • 前 박닝 베트남 제1체육대학교, 강사 (국제 협력요원) 
  • 前 한국 도핑방지위원회(Korea Anti-Doping Association)도핑검사관
  • 前 울산과학기원(UNIST) 박사후 연구원
  • 前 National Institute of Health, National Institue on Aging, 박사후 연구원
실적

[학술지 논문]

 

Distinct effect of exercise modes on mood-related behavior in mice
KH Yuk, …HY Moon
Biochemical and Biophysical Research Communications , 2023
 
Urinary extracellular vesicle as a potential biomarker of exercise-induced fatigue in young adult males
S Park, HY Moon
European Journal of Applied Physiology 122 (10), 2175-2188, 2022
 
Effects of lifelong spontaneous exercise on skeletal muscle and angiogenesis in super-aged mice
KW Baek, SJ Kim, BG Kim, YK Jung, YS Hah, HY Moon, JI Yoo, JS Park
Plos one 17 (8), e0263457, 2022
 
Muscle fiber type-dependence effect of exercise on genomic networks in aged mice models
SM Lee, MC Lee, WR Bae, KJ Yoon, HY Moon
Aging (Albany NY) 14 (8), 3337 1, 2022
 
Long‐term effects of adolescent sport experience, DRD2 and COMT genes, and their interaction on sport participation in adulthood
CG Lee, H Moon, JH Kang, JH Choi, JH Kwon
Brain and Behavior 12 (1), e2459, 2022
 
Effects of voluntary running wheel exercise-induced extracellular vesicles on anxiety
KJ Yoon, S Park, SH Kwak, HY Moon
Frontiers in Molecular Neuroscience 14, 665800 4, 2021
 
Effects of aerobic exercise training on systemic biomarkers and cognition in late middle-aged adults at risk for Alzheimer’s disease
JM Gaitán, HY Moon, M Stremlau, DB Dubal, DB Cook, OC Okonkwo
Frontiers in Endocrinology 12, 660181 26, 2021
 
The Role of Dopamine Receptor D2 in Bridging the Intention-Behavior Gap in Sport Participation
S Park, J Kwon, C Ahn, HS Cho, HY Moon, CG Lee
International Journal of Environmental Research and Public Health 18 (5), 2379 2, 2021
 
Exercise reduces metabolic burden while altering the immune system in aged mice
KJ Yoon, A Ahn, SH Park, SH Kwak, SE Kwak, W Lee, YR Yang, HY Moon
Aging (Albany NY) 13 (1), 1294 4, 2021
 
Lactate consumption mediates repeated high-intensity interval exercise-enhanced executive function in adult males
HS Cho, WS Lee, KJ Yoon, SH Park, HE Shin, YS Kim, H Chang, …
Physical Activity and Nutrition 24 (4), 15, 2020
 
Exercise-induced recovery of plasma lipids perturbed by ageing with nanoflow UHPLC-ESI-MS/MS
KU Kim, KJ Yoon, S Park, JC Lee, HY Moon, MH Moon
Analytical and Bioanalytical Chemistry 412, 8003-8014 6, 2020
 
Effects of treadmill exercise on the regulation of tight junction proteins in aged mice
HE Shin, SE Kwak, D Di Zhang, J Lee, KJ Yoon, HS Cho, HY Moon
Experimental Gerontology 141, 111077 11, 2020
 
The effects of dopamine receptor genes on the trajectories of sport participation from adolescence through young adulthood
CG Lee, H Moon, S Park
Annals of Human Biology 47 (3), 256-262 7, 2020
 
Exercise‐induced Extracellular Vesicles’ Effect on Stress.
KJ Yoon, HS Cho, WS Lee, HY Moon
The FASEB Journal 34 (S1), 1-1 , 2020
 
Neural maturation enhanced by exercise-induced extracellular derivatives
HY Moon, KJ Yoon, WS Lee, HS Cho, DY Kim, JS Kim
Scientific Reports 10 (1), 1-11 7, 2020
 
Exercise-induced changes of gene expression in the cerebellum of aged mice
M Lee, HS Cho, KJ Yoon, WS Lee, HY Moon
Biochemical and Biophysical Research Communications 521 (4), 952-956 7, 2020
 
Physical activity and brain plasticity
HY Moon, H Van Praag
Journal of exercise nutrition & biochemistry 23 (4), 23 6, 2019
 
Effect of a single bout of exercise on autophagy regulation in skeletal muscle of high-fat high-sucrose diet-fed mice
D Zhang, JH Lee, SE Kwak, HE Shin, Y Zhang, HY Moon, DM Shin, …
Journal of Obesity & Metabolic Syndrome 28 (3), 175 9, 2019
 
Effects of 10-week treadmill exercise on the improvement of obesity-induced autophagy dysregulation in arterial endothelial cells of mice
JS Kim, TB Jeon, KW Baek, JI Yoo, SH An, HY Moon
Exercise Science 28 (3), 263-269 1, 2019
 
Potential role of exercise-induced glucose-6-phosphate isomerase in skeletal muscle function
SE Kwak, HE Shin, D Di Zhang, J Lee, KJ Yoon, JH Bae, HY Moon
Journal of Exercise Nutrition & Biochemistry 23 (2), 28 4, 2019
 
Exercise-induced AMPK activation is involved in delay of skeletal muscle senescence
KJ Yoon, D Zhang, SJ Kim, MC Lee, HY Moon
Biochemical and biophysical research communications 512 (3), 604-610 33, 2019
 
Effects of acute aerobic exercise on the early stage of energy metabolism related gene expression in mouse gastrocnemius: microarray analysis
JH Lee, D Zhang, SE Kwak, HE Shin, HY Moon, W Song
Exercise Science 28 (1), 49-59 1, 2019
 
Conditioned media from AICAR-treated skeletal muscle cells increases neuronal differentiation of adult neural progenitor cells
HY Moon, S Javadi, M Stremlau, KJ Yoon, B Becker, SU Kang, X Zhao
Neuropharmacology 145, 123-130 24, 2019
 
Differential expression of genes in the subgranular zone and granular cell layer of the hippocampus after running
H Moon
Journal of Exercise Nutrition & Biochemistry 22 (4), 1 2, 2018
 
On the run for hippocampal plasticity
HY Moon, H van Praag
Cold Spring Harbor perspectives in medicine 8 (4), a029736 117, 2018
 
Exercise in a pill: the latest on exercise-mimetics
D Guerrieri, HY Moon, H van Praag
Brain Plasticity 2 (2), 153-169 61, 2017
 
Running-induced systemic cathepsin B secretion is associated with memory function
HY Moon, A Becke, D Berron, B Becker, N Sah, G Benoni, E Janke
Cell metabolism 24 (2), 332-340 388, 2016
 
Apolipoprotein a1 increases mitochondrial biogenesis through AMP-activated protein kinase
P Song, Y Kwon, K Yea, HY Moon, JH Yoon, J Ghim, H Hyun, D Kim
Cellular Signalling 27 (9), 1873-1881 21, 2015
 
Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling
YR Yang, DH Kim, YK Seo, D Park, HJ Jang, SY Choi, YH Lee, GH Lee, …
Oncotarget 6 (14), 12529 66, 2015
 
Muscle over mind
HY Moon, van Praag H.
Cell Metabolism 20 (4), 560-562 27, 2014
 
Involvement of exercise-induced macrophage migration inhibitory factor in the prevention of fatty liver disease
HY Moon, P Song, CS Choi, SH Ryu, PG Suh
The Journal of endocrinology 218 (3), 339 23, 2013
 
Emodin regulates glucose utilization by activating AMP-activated protein kinase
P Song, JH Kim, J Ghim, JH Yoon, A Lee, Y Kwon, H Hyun, HY Moon
Journal of Biological Chemistry 288 (8), 5732-5742 69, 2013
 
The androgenic anabolic steroid tetrahydrogestrinone produces dioxin-like effects via the aryl hydrocarbon receptor
HY Moon, SH Kim, SH Ryu, PG Suh
Toxicology In Vitro 26 (7), 1129-1133 5, 2012
 
Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise
HY Moon, SH Kim, YR Yang, P Song, HS Yu, HG Park, O Hwang
Proceedings of the National Academy of Sciences 109 (32), 13094-13099 9 5, 2012
 
O‐GlcNAcase is essential for embryonic development and maintenance of genomic stability
YR Yang, M Song, H Lee, Y Jeon, EJ Choi, HJ Jang, HY Moon, HY Byun, …
Aging cell 11 (3), 439-448, 2012

[최근 연구과제]

 

  • 2022.6 ~ 2025.5: 운동 유도 호중구의 암제어 연구, 이공 학제간 융합연구 (National Research Foundation)
  • 2022.6 ~ 2028.2: 인공지능 기반 뇌혈관질환 디지털 의료 시스템 개발 연구 (지역혁신 선도연구센터, RLRC)
  • 2020.3  ~ 2023. 2: 운동 후 혈액에서 유래된 세포외 소포체가 지속적이고 예측 불가능한 스트레스에 의해 유도된 우울증 마우스의 정서조절에 관한 연구  
  • 2017.3 ~ 2020.2: Research on the effect of exercise-induced Exosome on hippocampal neurogenesis, behavioral changes and its underlying mechanism (National Research Foundation)